Based on some request, I have updated the analysis.
It now includes:
1. Brief comparison between EM and HP.
2. Comparison between Heart of Depths, Thundering Fury, 2-Wanderer + 2-Crimson, and Bloodstained.
3. Vaporize simulation.
4. Comparison between Dragonspine spear and Black Tassel.
5. R2-R5 Dragon's Bane on Vaporized comp.
Go here to check it out
I hope it answers some of your questions!
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A short comparison between AA and Skill talent up:

Original: All Talent at Lv6.
Skill: Skill talent at Lv8, the rest are Lv6.
AA: Normal attack talent at Lv8, the rest are Lv6.
Comparing them against each other, and we have:

So upgrading AA result in ~4% higher overall damage output than upgrading skill.
Please note that this is a short comparison. So take it with a grain of salt.


